MOSC2 Antibody

Western Blot: MOSC2 Antibody [NBP2-19381] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE gel, diluted at 1:5000.

Immunocytochemistry/Immunofluorescence: MOSC2 Antibody [NBP2-19381] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.

Immunohistochemistry-Paraffin: MOSC2 Antibody [NBP2-19381] - Human colon carcinoma, using MOSC2 antibody at 1:250 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

MOSC2 Antibody Summary

• Description: Novus Biologicals Rabbit MOSC2 Antibody (NBP2-19381) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MOSC2. The exact sequence is proprietary.
• Localization: Mitochondrion outer membrane; Peripheral membrane protein
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MARC2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:1000-1:10000
• Theoretical MW: 38 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for MOSC2 Antibody

• FLJ20605
• MOCO sulphurase C-terminal domain containing 2
• MOSC domain-containing protein 2, mitochondrial
• RP11-270A6.1

Background

Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: MARC2
• Uniprot:
  • Q969Z3(Human)