Recombinant Human MIA2 Protein

Product Discontinued

Recombinant Human MIA2 Protein Summary

• Description: Recombinant protein containing 101 amino acids for Human MIA2
  
  

  Source:E. coli
  Amino Acid Sequence:(Q96PC5) - MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L

• Preparation Method: Determined to be >97% pure by SDS-PAGE
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: MIA2
• Purity: >97%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 11.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C.
• Buffer: Lyophilized from 20 mM phosphate buffer (pH 7.4), 150 mM NaCl.
• Concentration: Lyoph
• Purity: >97%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute in sterile H2O to >100 ug/ml. Reconstituted MIA2 protein should be stored in working aliquots at -20C.

Alternate Names for Recombinant Human MIA2 Protein

• FLJ22404
• melanoma inhibitory activity 2
• melanoma inhibitory activity protein 2

Background

MIA2 performs as a tumour suppressor in hepatocellular carcinoma. MIA2 is a novel acute phase protein which its expression is found in the liver and reacts to liver damage in chronic liver diseases and is considerably higher in severe fibrosis patients . MIA2 is induced by IL6, TGF-b and conditioned medium from activated hepatic stellate cells. MIA2 is is mainly expressed in hepatocytes. MIA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain consisting of 101 amino having a total molecular mass of 11.5 kDa. The MIA2 is purified by proprietary chromatographic techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: MIA2