Recombinant Human LSM2 His Protein

SDS-Page: Recombinant Human LSM2 Protein [NBP1-99048] - 15% SDS-PAGE (3ug)

SDS-Page: Recombinant Human LSM2 Protein [NBP1-99048] - 15% SDS-PAGE (3ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human LSM2 His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-95 of Human LSM2
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMLFYSF FKSLVGKDVV VELKNDLSIC GTLHSVDQYL NIKLTDISVT DPEKYPHMLS VKNCFIRGSV VRYVQLPADE VDTQLLQDAA RKEALQQKQ

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: LSM2
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 13.4 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 5mM DTT, 40% glycerol, 200 mM NaCl
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human LSM2 His Protein

• C6orf28chromosome 6 open reading frame 28
• G7B
• LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
• Protein G7b
• Small nuclear ribonuclear protein D homolog
• snRNP core Sm-like protein Sm-x5
• snRNP
• U6 snRNA-associated Sm-like protein LSm2
• YBL026W

Background

LSM2 (U6 snRNA-associated Sm-like protein LSm2) belongs to the snRNP Sm proteins family. Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA. It is involved in pre-mRNA splicing. Recombinant human LSM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: LSM2