LMAN1L/SLAMP Antibody [Alexa Fluor® 350]

• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 350

LMAN1L/SLAMP Antibody [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant rat LMAN1L/SLAMP
  Arg33-Thr436
  Accession # Q5FB95
• Specificity: Detects rat LMAN1L/SLAMP in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

SLAMP (Sublingual acinar membrane protein; also LMAN1L) is a 50‑60 kDa protein that likely is a member of the animal L‑type lectin family of proteins. It is expressed exclusively by mucous secreting cells in the ER‑Golgi compartment. SLAMP likely plays a role in the intracellular trafficking of glycoproteins, possibly by binding mannose residues. Mature rat SLAMP is a 475 amino acid (aa) type I transmembrane protein that contains a 409 aa extracellular region (aa 29‑437) and a 43 aa cytoplasmic domain (aa 461‑503). Over aa 33‑436, rat SLAMP shares 89% aa identity with mouse SLAMP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.