LARGE Antibody - BSA Free

Western Blot: LARGE Antibody [NBP3-41323] - Sample: Recombinant protein.

Immunohistochemistry-Paraffin: LARGE Antibody [NBP3-41323] - Used in DAB staining on fromalin fixed paraffin- embedded Kidney tissue

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.66 mg/ml

LARGE Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit LARGE Antibody - BSA Free (NBP3-41323) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunized with recombinant Human LARGE (Uniprot#: O95461; Thr25-Ala178 (Uniprot#: O95461)
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LARGE1
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.01M PBS, pH7.4, 50% glycerol
• Preservative: 0.05% Proclin 300
• Concentration: 0.66 mg/ml
• Purity: Antigen and protein A Affinity-purified

Alternate Names for LARGE Antibody - BSA Free

• Acetylglucosaminyltransferase-like 1A
• acetylglucosaminyltransferase-like protein
• glycosyltransferase-like protein LARGE1
• LARGE
• LARGE1
• like-acetylglucosaminyltransferase
• like-glycosyltransferase
• MDC1D
• MDDGA6
• MDDGB6
• xylosyl- and glucuronyltransferase LARGE1

Background

This gene encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. The protein encoded by this gene is the glycotransferase that adds the final xylose and glucuronic acid to alpha-dystroglycan and thereby allows alpha-dystroglycan to bind ligands including laminin 211 and neurexin. Mutations in this gene cause several forms of congenital muscular dystrophy characterized by cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2018]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LARGE1