Kallikrein 5 Antibody

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Western Blot: Kallikrein 5 Antibody [NB100-58963] - Staining of Human Brain (Cerebellum) (A), Mouse Brain (B) and Rat Brain (C) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Kallikrein 5 Antibody Summary

Immunogen
Peptide with sequence KAGRDSCQGD corresponding to internal region according to NP_036559.1.
Epitope
KAGRDSCQGD
Specificity
Reported variants represent identical protein (NP_036559.1; NP_001070959.1; NP_001070960.1).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
KLK5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1-3 ug/ml
  • Peptide ELISA 1:1000
Application Notes
WB: Approx. 37 kDa band observed in human prostate lysates (calculated MW of 32.0 kDa band according to NP_036559.1).
Control
Human Prostate Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publication using NB100-58963.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Kallikrein 5 Antibody

  • EC 3.4.21
  • EC 3.4.21.4
  • Kallikrein 5
  • Kallikrein-like protein 2
  • kallikrein-related peptidase 5
  • KLK5
  • KLKL2
  • KLK-L2
  • KLK-L2EC 3.4.21.-
  • SCTE
  • SCTEkallikrein-5
  • Stratum corneum tryptic enzyme

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Kallikrein 5 Antibody (NB100-58963)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

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Bioinformatics

Gene Symbol KLK5
Entrez
Uniprot