IRF2 Antibody [Alexa Fluor™ Plus 594]

• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor Plus 594

IRF2 Antibody [Alexa Fluor™ Plus 594] Summary

• Specificity: Detects endogenous human and mouse IRF2 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Interferon Regulatory Factor 2 (IRF2) belongs to the interferon regulatory transcription factor family. IRF2 functions as a regulator of type I interferons by influencing cellular proliferation and immune response through transcriptional regulation. IRF2 competitively inhibits IRF1 gene activation, as well as, stimulating transcription on its own. Overexpression of IRF2 in NIH3T3 cells leads to transformation, whereas, loss of IRF2 expression in knock out mice leads to a variety of abnormalities including loss of NK cells due to increased apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.