IA-2/PTPRN Antibody (815811) [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 815811
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

IA-2/PTPRN Antibody (815811) [mFluor Violet 500 SE] Summary

• Immunogen: E. coli-derived recombinant human IA-2/PTPRN
  Val35-Arg575
  Accession # Q16849
• Specificity: Detects human IA-2/PTPRN in ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTPRN
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IA-2/PTPRN Antibody (815811) [mFluor Violet 500 SE]

• CA 512
• EC 3.1.3.48
• FLJ16131
• IA2
• IA-2
• IA-2/PTP
• ICA 512
• ICA3
• ICA512
• islet cell antigen 2
• Islet cell antigen 512
• Islet cell autoantigen 3
• protein tyrosine phosphatase, receptor type, N
• protein tyrosine phosphatase-like N
• PTP IA-2
• PTPRN
• receptor-type tyrosine-protein phosphatase-like N
• R-PTP-N

Background

PTPRN is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRN