HYAL3 Antibody (3A3)

Product Discontinued

HYAL3 Antibody (3A3) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: HYAL3 (AAH05896, 1 a.a. ~ 417 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MTTQLGPALVLGVALCLGCGQPLPQVPERPFSVLWNVPSAHCEARFGVHLPLNSLGIIANRGQHFHGQNMTIFYKNQLGLYPYFGPRGTAHNGGIPQALPLDRHLALAAYQIHHSLRPGFAGPAVLDWEEWCPLWAGNWGRRRAYQAASWAWAQQVFPDLDPQEQLYKAYTGFEQAARALMEDTLRVAQALRPHGLWGFYHYPACGNGWHSMASNYTGRCHAATLARNTQLHWLWAASSALFPSIYLPPRLPPAHHQAFVRHRLEEAFRVALVGHRHPLPVLAYVRLTHRRSGRFLSQDDLVQSIGVSAALGAAGVVLWGDLSLSSSEEECWHLHDYLVDTLGPYVINVTRAAMACSHQRCHGHGRCARRDPGQMEAFLHLWPDGSLGDWKSFSCHCYWGWAGPTCQEPRPGPKEAV
• Localization: Secreted. Lysosome.
• Specificity: HYAL3 - hyaluronoglucosaminidase 3
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: HYAL3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Antibody reactivity against recombinant protein on ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HYAL3 Antibody (3A3)

• EC 3.2.1.35
• HYAL-3
• hyaluronidase-3
• hyaluronoglucosaminidase 3
• Hyaluronoglucosaminidase-3
• LUCA14
• LuCa-3
• LUCA3LUCA-3
• Lung carcinoma protein 3
• Minna14

Background

This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HYAL3 Antibody (H00008372-M01)(1)

Publication using H00008372-M01

• Monzon ME, Manzanares D, Schmid N et al. Hyaluronidase Expression and Activity Is Regulated by Pro-Inflammatory Cytokines in Human Airway Epithelial Cells. Am J Respir Cell Mol Biol 2008-04-03 [PMID: 18390475]

Bioinformatics

• Gene Symbol: HYAL3
• Entrez:
  • 8372(Human)
• OMIM:
  • 604038(Human)
• Uniprot:
  • AAH05896(Human)