Recombinant Human Hsp70 interacting protein HIP Protein

SDS-Page: Recombinant Human Hsp70 interacting protein HIP Protein [NBC1-19066] - > 90% by SDS - PAGE

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human Hsp70 interacting protein HIP Protein Summary

• Description: An un-tagged recombinant protein corresponding to the amino acids 1-369 of Human Hsp70 interacting protein HIP
  
  

  Source: E.coli

  Amino Acid Sequence: MDPRKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP DSKKVEEDLK ADEPSSEESD LEIDKEGVIE PDTDAPQEMG DENAEITEEM MDQANDKKVA AIEALNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIRD CDRAIEINPD SAQPYKWRGK AHRLLGHWEE AAHDLALACK LDYDEDASAM LKEVQPRAQK IAEHRRKYER KREEREIKER IERVKKAREE HERAQREEEA RRQSGAQYGS FPGGFPGGMP GNFPGGMPGM GGGMPGMAGM PGLNEILSDP EVLAAMQDPE VMVAFQDVAQ NPANMSKYQS NPKVMNLISK LSAKFGGQA

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: ST13
• Purity: >90%, by SDS-PAGE
• Endotoxin Note: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 41.3 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 0.1 M NaCl, 10% glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human Hsp70 interacting protein HIP Protein

• AAG2
• aging-associated protein 2
• FAM10A1FAM10A4
• heat shock 70kD protein binding protein
• Hip
• HIPFLJ27260
• HOP
• hsc70-interacting protein
• Hsp70-interacting protein
• HSPABP1
• P48MGC129952
• PRO0786
• Progesterone receptor-associated p48 protein
• Protein FAM10A1
• Putative tumor suppressor ST13
• Renal carcinoma antigen NY-REN-33
• SNC6HSPABP
• suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
• suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein)
• Suppression of tumorigenicity 13 protein

Background

HIP1 (Hsc70-interacting protein), also known as ST13, is a co-chaperone to the major heat shock proteins, Hsp70 and Hsp90, and appears in early receptor complexes. Through mutual binding to both Hsp70 and Hsp90, Hip functions as an adaptor that can integrate Hsp70 and Hsp90 interactions. Also, Hip has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. Recombinant human HIP1 was expressed in E.coli and purified by using conventional chromatography

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: ST13