Hsp70 interacting protein HIP Antibody (5C6) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB, ELISA, Flow, ICC/IF
• Clone: 5C6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

Hsp70 interacting protein HIP Antibody (5C6) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: Recombinant human Hsp70 interacting protein HIP (1-369aa) purified from E. coli
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ST13
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Hsp70 interacting protein HIP Antibody (5C6) [CoraFluor™ 1]

• AAG2
• aging-associated protein 2
• FAM10A1FAM10A4
• heat shock 70kD protein binding protein
• Hip
• HIPFLJ27260
• HOP
• hsc70-interacting protein
• Hsp70-interacting protein
• HSPABP1
• P48MGC129952
• PRO0786
• Progesterone receptor-associated p48 protein
• Protein FAM10A1
• Putative tumor suppressor ST13
• Renal carcinoma antigen NY-REN-33
• SNC6HSPABP
• suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
• suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein)
• Suppression of tumorigenicity 13 protein

Background

Hsp70 interacting protein HIP is encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ST13