Histone H1 Antibody (HH1/957) [DyLight 594]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
HH1/957
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

Histone H1 Antibody (HH1/957) [DyLight 594] Summary

Immunogen
Recombinant full-length human Histone H1 protein
Localization
Nuclear
Marker
Nuclear Marker
Specificity
Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
H1-1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Histone H1 Antibody (HH1/957) [DyLight 594]

  • H1 histone family, member 1
  • H1.1
  • H1A
  • H1F1HIST1
  • histone 1, H1a
  • histone cluster 1, H1a
  • histone H1.1
  • MGC126642
  • MGC138345

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47754AF350
Alexa Fluor 405 NBP2-47754AF405
Alexa Fluor 488 NBP2-47754AF488
Alexa Fluor 532 NBP2-47754AF532
Alexa Fluor 594 NBP2-47754AF594
Alexa Fluor 647 NBP2-47754AF647
Alexa Fluor 700 NBP2-47754AF700
Alexa Fluor 750 NBP2-47754AF750
Allophycocyanin NBP2-47754APC
Biotin NBP2-47754B
DyLight 350 NBP2-47754UV
DyLight 405 NBP2-47754V
DyLight 488 NBP2-47754G
DyLight 550 NBP2-47754R
DyLight 594 NBP2-47754DL594
DyLight 650 NBP2-47754C
DyLight 680 NBP2-47754FR
DyLight 755 NBP2-47754IR
FITC NBP2-47754F
HRP NBP2-47754H
Janelia Fluor 549 NBP2-47754JF549
Janelia Fluor 646 NBP2-47754JF646
PE NBP2-47754PE
PerCP NBP2-47754PCP

Additional Histone H1 Products

Array NBP2-47754DL594

Bioinformatics Tool for Histone H1 Antibody (NBP2-47754DL594)

Discover related pathways, diseases and genes to Histone H1 Antibody (NBP2-47754DL594). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Histone H1 Antibody (NBP2-47754DL594)

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Research Areas for Histone H1 Antibody (NBP2-47754DL594)

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Blogs on Histone H1.

Histone H3
Eukaryotic chromosomes are formed through the highly organized and structural wrapping of DNA genetic material around histone proteins into the classic "bead on a string" globular structure of nucleosomes. The histone family consists of five family me...  Read full blog post.

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Bioinformatics

Gene Symbol H1-1