GPR64 Antibody

Immunohistochemistry-Paraffin: GPR64 Antibody [NLS1262] - Human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: GPR64 Antibody [NLS1262] - Analysis of anti-GPR64 antibody with human brain, glioblastoma.

Immunohistochemistry-Paraffin: GPR64 Antibody [NLS1262] - Anti-GPR64 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: GPR64 Antibody [NLS1262] - Lung, Adenocarcinoma

Immunohistochemistry-Paraffin: GPR64 Antibody [NLS1262] - Epididymis

Product Discontinued

GPR64 Antibody Summary

• Immunogen: Synthetic 20 amino acid peptide from C-terminus of human GPR64.
• Localization: Cell membrane; Multi pass membrane protein.
• Specificity: Human GPR64. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Equine (90%), Canine (90%), Bat (90%), Bovine (95%), Rabbit (95%), Opossum (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADGRG2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Panda (95%), Porcine (80%), Platypus (80%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GPR64 Antibody

• EDDM6
• epididymis-specific (seven transmembrane family)
• G protein-coupled receptor 64
• GPR64
• HE6
• MGC104454
• MGC138738
• TM7LN2

Background

GPR64 is an Orphan-B GPCR with an unknown ligand. HE6 is endogenously cleaved into two pieces at the GPCR proteolytic site (GPS) located adjacent to the first transmembrane helix as a mechanism to compartmentalize the cell adhesion and GPCR activation functions. GPR64 has been reported in the epididymis. ESTs have been isolated from embryo, kidney, placenta, skeletal muscle, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADGRG2
• Entrez:
  • 10149(Human)
• Uniprot:
  • Q8IZP9(Human)