GPAA1 Antibody [DyLight 550]

Product Discontinued

GPAA1 Antibody [DyLight 550] Summary

• Immunogen: glycosylphosphatidylinositol anchor attachment protein 1 homolog(yeast). (Uniprot# O43292)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPAA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GPAA1 Antibody [DyLight 550]

• anchor attachment protein 1 (Gaa1p, yeast) homolog
• GAA1 protein homolog
• GAA1glycophosphatidylinositol anchor attachment 1
• glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)
• GPAA1P anchor attachment protein 1 homolog (yeast)
• GPAA1P anchor attachment protein 1 homolog
• GPI anchor attachment protein 1
• GPI transamidase subunit
• hGAA1glycosylphosphatidylinositol anchor attachment 1 protein

Background

The GPAA1 gene codes for a post-translational glycosylphosphatidylinositol (GPI) anchor attachment 1 protein at the GPI transfer step but is not essential for GPI synthesis. This protein functions as a general mechanism to link proteins to the cell surface membrane and is coded before/during the formation of the carbonyl intermediate. Isoform 1 is 621 amino acids in length at 67 kDA while isoform 2 exists at 561 amino acids long at 61 kDA. GPAA1 participates in various metabolic pathways as well as post-translational protein modification through interactions with genes PRR13, ALPP, PIN1, EIF3E, and GRIK5. GPAA1 has been investigated regarding various diseases such as ataxia, hepatocellular carcinoma, and breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPAA1