Exostosin-like 2/EXTL2 Antibody

ELISA: Exostosin-like 2/EXTL2 Antibody [30310002]

Product Discontinued

Exostosin-like 2/EXTL2 Antibody Summary

• Immunogen: This antibody is specific for the C Terminus Region of the target protein.
• Specificity: This product is specific for Human EXTL2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EXTL2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
• Application Notes: This antibody is useful in ELISA and Immunohistochemistry-Paraffin.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for Exostosin-like 2/EXTL2 Antibody

• Alpha-1,4-N-acetylhexosaminyltransferase EXTL2
• alpha-1,4-N-acteylhexosaminyltransferase
• Alpha-GalNAcT EXTL2
• EC 2.4.1.223
• exostoses (multiple)-like 2
• Exostosin like 2
• Exostosin-like 2
• EXTL2
• EXTR2
• EXT-related protein 2
• Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
• processed exostosin-like 2

Background

EXTL2 glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Exostosin-like 2/EXTL2 Antibody (30310002)(2)

Publications using 30310002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: EXTL2
• Entrez:
  • 2135(Human)
• Uniprot:
  • Q9UBQ6(Human)