DNAL1 Antibody - BSA Free

Western Blot: DNAL1 Antibody [NBP1-76932] - 3T3 cell lysate with DNAL1 antibody at (A) 1 and (B) 2 ug/ml.

Immunocytochemistry/ Immunofluorescence: DNAL1 Antibody - BSA Free [NBP1-76932] - Immunofluorescence of DNAL1 in 3T3 cells with DNAL1 antibody at 20 ug/mL.Green: DNAL1 Antibody Blue: DAPI staining

Immunocytochemistry/ Immunofluorescence: DNAL1 Antibody - BSA Free [NBP1-76932] - Immunocytochemistry of DNAL1 in 3T3 cells with DNAL1 antibody at 2.5 ug/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

DNAL1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit DNAL1 Antibody - BSA Free (NBP1-76932) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human DNAL1. The immunogen is located within the last 50 amino acids of DNAL1. Amino Acid Squence: KKLDGTPVIKEDEEEDN
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DNAL1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  DNAL1 Peptide (NBP1-76932PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for DNAL1 Antibody - BSA Free

• C14orf168MGC12435,1700010H15RiK
• chromosome 14 open reading frame 168
• dynein light chain 1, axonemal
• dynein, axonemal, light chain 1

Background

DNAL1 was identified as a potential candidate gene for primary ciliary dyskinesia (PCD), a genetically heterologous disorder characterized by chronic infections of the upper and lower airways that often leads to permanent lung damage, randomization of left/right body symmetry, and reduced fertility. DNAL1 is reported to be expressed solely in tissues carrying motile cilia for flagella and interacts with DNAH5, a protein that when mutated has been shown to result in PCD. It has been suggested that DNAL1 serves a regulatory function for DNAH5 activity in outer dynein arms of sperm flagella, respiratory cilia, and ependymal cilia. DNAL1 has also been recently identified as an HIV dependency factor (HDF), suggesting that DNAL1 may be an important drug target in HIV treatment. At least two isoforms of DNAL1 are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DNAL1
• Uniprot:
  • NP_113615(Human)