DDX3Y Antibody

Product Discontinued

DDX3Y Antibody Summary

• Immunogen: The antiserum was produced against synthesized peptide derived from human DDX3Y. The immunogen region is: N-terminal.
• Specificity: DDX3Y Antibody detects endogenous levels of total DDX3Y protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DDX3Y
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:20000
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100

Reactivity Notes

Human,Mouse

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for DDX3Y Antibody

• ATP-dependent RNA helicase DDX3Y
• DBYEC 3.6.4.13
• DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
• DEAD box protein 3, Y-chromosomal
• DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome
• EC 3.6.1

Background

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DDX3Y
• Uniprot:
  • O15523(Human)