COG1 Antibody

Western Blot: COG1 Antibody [NBP1-28468] - Staining of Human Cerebellum lysate (35 ug protein in RIPA buffer) with antibody at 0.1 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence. Approx. 110 kDa band observed (calculated MW of 109 kDa band according to NP_061184.1). An additional band of unknown identity was also consistently observed at 45 kDa. This band was successfully blocked by incubation with the immunizing peptide.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

COG1 Antibody Summary

• Description: Novus Biologicals Goat COG1 Antibody (NBP1-28468) is a polyclonal antibody validated for use in WB and ELISA. Anti-COG1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This COG1 Antibody was developed against a peptide with sequence C-KAKSTRNIETKAQ corresponding to internal region according to NP_061184.1.
• Epitope: C terminus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: COG1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:64000
  • Western Blot 0.1 - 0.3 ug/mL

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for COG1 Antibody

• COG complex subunit 1
• component of oligomeric golgi complex 1CDG2G
• conserved oligomeric Golgi complex subunit 1
• KIAA1381DKFZp762L1710
• LDLBconserved oligomeric Golgi complex protein 1
• low density lipoprotein receptor defect B complementing

Background

The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for COG1 Antibody (NBP1-28468)(1)

Publication using NBP1-28468

• Vasile E, Oka T, Ericsson M et al. IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex. Exp Cell Res 2006-10-01 [PMID: 16857184]

Bioinformatics

• Gene Symbol: COG1
• Entrez:
  • 9382(Human)
  • 228357(Mouse)
  • 83469(Rat)
• Uniprot:
  • NP_061184.1(Human)