clarin 1 Antibody

Product Discontinued

clarin 1 Antibody Summary

• Immunogen: In vivo generated recombinant protein fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CLRN1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:2000
  • Immunocytochemistry/ Immunofluorescence 1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Western Blot
• Application Notes: Use in Immunohistochemistry-Frozen and westernblot reported in scientific literature (PMID 24045267). Use in Immunohistochemistry reported in scientific literature (PMID 26180195)

Reactivity Notes

Zebra Fish

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for clarin 1 Antibody

• clarin 1
• clarin-1
• USH3
• USH3AUsher syndrome type-3 protein
• Usher syndrome 3A

Background

The clarin 1 gene encodes a protein that contains a cytosolic N-terminus, multiple helical transmembrane domains, and an endoplasmic reticulum membrane retention signal, TKGH, in the C-terminus. The encoded protein may be important in development and homeostasis

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for clarin 1 Antibody (42720002)(2)

Publications using 42720002

• Geng R, Omar A, Gopal SR et al. Modeling and Preventing Progressive Hearing Loss in Usher Syndrome III. Sci Rep. 2017-10-18 [PMID: 29044151] (ICC/IF, Zebrafish)
• Phillips JB, Vastinsalo H, Wegner J et al. The cone-dominant retina and the inner ear of zebrafish express the ortholog of CLRN1, the causative gene of human Usher syndrome type 3A. Gene Expr Patterns. 2013-09-14 [PMID: 24045267] (IHC-Fr, WB, ICC/IF, Zebrafish)

FAQs for clarin 1 Antibody (42720002). (Showing 1 - 2 of 2 FAQs).

1. Is this antibody generated to target C-terminus or N-terminus of the zebra fish clarin1 protein? And the target amino acid sequence? Whether you have tried this antibody with western blotting zebra fish protein lysate?
   • The amino acid range for the immunogen for 42720002 falls between amino acids 30-101.
2. I just wonder what is the final volume this antibody supplies: clarin 1 Antibody 0.05 mg (42720002).
   • The current lot, 3149004A01, is provided at 1.0mg/ml.

Bioinformatics

• Gene Symbol: CLRN1
• Uniprot:
  • Q6DGA8(Zebrafish)