Human Cav1.3 - Ready-To-Use ELISA Kit (Colorimetric)

ELISA: Human Cav1.3 - Ready-To-Use ELISA Kit (Colorimetric) [NBP3-31162] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Tissue homogenates and other biological fluids
• Standard Curve Range: 0.312 - 20 ng/mL (example only; lot dependent)
• Sensitivity: 0.121 ng/mL (example only; lot dependent)

Human Cav1.3 - Ready-To-Use ELISA Kit (Colorimetric) Summary

• Description: The Ready-To-Use ELISA kit offers pre-diluted detection reagents and a shorter experimental time.
  Assay Length: 3 hours
• Standard Curve Range: 0.312 - 20 ng/mL (example only; lot dependent)
• Sensitivity: 0.121 ng/mL (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Inter-Assay: %CV < 12 (example only; lot dependent)
• Intra-Assay: %CV < 10 (example only; lot dependent)
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: CACNA1D

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Cav1.3 - Ready-To-Use ELISA Kit (Colorimetric)

• CACH3
• CACN4
• CACN4calcium channel, neuroendocrine/brain-type, alpha 1 subunit
• CACNA1D
• CACNL1A2
• CACNL1A2voltage-dependent L-type calcium channel subunit alpha-1D
• Calcium channel, L type, alpha-1 polypeptide, isoform 2
• calcium channel, voltage-dependent, L type, alpha 1D subunit
• Cav1.3
• CCHL1A2
• CCHL1A2voltage-gated calcium channel alpha 1 subunit
• L type, alpha-1 polypeptide
• voltage-gated calcium channel alpha subunit Cav1.3
• Voltage-gated calcium channel subunit alpha Cav1.3

Background

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).; Subcellular location: Membrane; Multi-pass membrane protein.; Tissue specificity: Expressed in pancreatic islets and in brain, where it has been seen in hippocampus, basal ganglia, habenula and thalamus. No expression in skeletal muscle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CACNA1D