beta-Arrestin 2 Antibody Blocking Peptide Summary
| Specificity |
This peptide is specific for NBP2-24569 only. |
| Protein/Peptide Type |
Antibody Blocking Peptide |
| Gene |
ARRB2 |
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This peptide is useful as a blocking peptide for NBP2-24569. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles. |
| Buffer |
Peptide dissolved in dH20. Contains no BSA. |
| Preservative |
No Preservative |
| Concentration |
1 mg/ml |
Alternate Names for beta-Arrestin 2 Antibody Blocking Peptide
Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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