Hu, Mu, Rt, Bv, Ca, Ch, Eq, Pm, Xp, ZeApplications:
WB, Simple Western, IHC, IHC-PHost:
WB, ELISA, ICC/IF, IHC, IHC-P, PLAHost:
Hu, Mu, RtApplications:
WB, ELISA, ICC/IFHost:
WB, ELISA, IP, PA, AP
Applications: WB, ELISA, PA, AP
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
PTMs for beta-Arrestin 2
Learn more about PTMs related to beta-Arrestin 2.Phosphorylation
Bioinformatics Tool for beta-Arrestin 2
Discover related pathways, diseases and genes to beta-Arrestin 2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.