Angiopoietin-like protein 8/Betatrophin Antibody (910248) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clone: 910248
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

Angiopoietin-like protein 8/Betatrophin Antibody (910248) [Alexa Fluor® 594] Summary

• Immunogen: Human Angiopoietin-like Protein 8/Betatrophin synthetic peptide with sequences corresponding to the N-term region
  Accession # Q6UXH0
• Specificity: Detects human Angiopoietin-like Protein 8/Betatrophin in direct ELISA and Western Blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Angiopoietin-like protein 8/Betatrophin Antibody (910248) [Alexa Fluor® 594]

• Angiopoietin like Protein 8
• Angiopoietin-like Protein 8
• ANGPTL8
• Betatrophin
• C19orf80
• chromosome 19 open reading frame 80
• Gm6484
• hepatocellular carcinoma-associated gene TD26
• hepatocellular carcinoma-associated protein TD26
• Lipasin
• PRO1185
• PVPA599
• RIFL
• TD26
• UNQ599

Background

Betatrophin also known as C19orf80, ANGPTL8, and TD26, is a secreted hormone protein.  It is 198 amino acids (aa) in length, and shares 72% aa identity with mouse Betatrophin.  It is primarily expressed in the liver and adipose tissue and has been shown to be increased in the plasma of diabetic patients.  Additionally, Betatrophin has been demonstrated to increase the proliferation of beta cells in the pancreas of mice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.