Amiloride-sensitive cation channel 3 Antibody

Product Discontinued

Amiloride-sensitive cation channel 3 Antibody Summary

• Immunogen: Residues 3-18 of rat ASIC Beta. AGSELDEGDDSPRDLV
• Specificity: NB300-188 reacts with rat ASIC Beta.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Guinea Pig
• Gene: ASIC3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000
  • Immunohistochemistry-Paraffin 1:1000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Alternate Names for Amiloride-sensitive cation channel 3 Antibody

• ACCN3
• Acid-sensing ion channel 3
• Amiloride-sensitive cation channel 3
• amiloride-sensitive cation channel 3, testis
• ASIC3
• ASIC3hTNaC1
• DRASIC
• hASIC3
• modulatory subunit of ASIC2a
• Neuronal amiloride-sensitive cation channel 3
• proton-gated cation channel subunit
• SLNAC1
• Testis sodium channel 1
• TNAC1

Background

Two proton-gated channels, acid-sensing ionic channel (ASIC) and dorsal root ASIC (DRASIC), are known to be expressed by sensory neurons. These types of channels are of interest because low pH causes pain. ASIC Beta, a splice variant of ASIC, is found only in a subset of small and large diameter sensory neurons and is absent from sympathetic neurons or the central nervous system..

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ASIC3
• Entrez:
  • 79123(Rat)