IL-2 Products

Antibodies
ELISA Kits
Human IL-2 Quantikine ELISA K ...
Human IL-2 Quantikine ELISA Kit
D2050
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Mouse IL-2 DuoSet ELISA, 15 P ...
Mouse IL-2 DuoSet ELISA, 15 Plate
DY402
Species: Mu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Human IL-2 DuoSet ELISA, 15 P ...
Human IL-2 DuoSet ELISA, 15 Plate
DY202
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Lysates
IL-2 Overexpression Lysate
IL-2 Overexpression Lysate
NBL1-11937
Species: Hu
Applications: WB
Proteins
Recombinant Human IL-2 Protei ...
Recombinant Human IL-2 Protein
202-IL
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse IL-2 Protei ...
Recombinant Mouse IL-2 Protein
402-ML
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Rat IL-2 Protein
Recombinant Rat IL-2 Protein
502-RL
Species: Rt
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

Human interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.

Bioinformatics

Entrez Human
Product By Gene ID 3558
Alternate Names
  • Aldesleukin
  • IL2
  • IL-2
  • IL-2lymphokine
  • interleukin 2
  • interleukin-2
  • involved in regulation of T-cell clonal expansion
  • Proleukin
  • T cell growth factor
  • T-cell growth factor
  • TCGF

Research Areas for IL-2

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Diabetes Research

Related IL-2 Blog Posts

Check out the latest blog posts on IL-2.
The role of HIF-2 alpha in the progression and therapy of clear cell renal cell carcinoma
HIF-2 alpha, also known as hypoxia-inducible factor 2, endothelial PAS domain protein-1, and member of PAS superfamily 2 is part of the HIF family of proteins.  The HIF family is composed of HIF-1, HIF-2 and HIF-3, where HIF-2 is a dimeric protein ...    Read more.
iNOS: The Nitric Oxide Boss
Nitric oxide (NO) is an inorganic, gaseous, and reactive free radical that acts as a biologic mediator in processes such as neurotransmission, vasorelaxation, and cytotoxicity. In addition, it has antimicrobial and anti-tumoral activities. NO producti...    Read more.
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