POT1 Products

POT1 Overexpression Lysate
POT1 Overexpression Lysate
Species: Hu
Applications: WB
POT1 Blocking Peptide
POT1 Blocking Peptide
Species: Hu
Recombinant Human POT1 Protei ...
Recombinant Human POT1 Protein
Species: Hu
Applications: WB, ELISA, PA, AP
POT1 Recombinant Protein Anti ...
POT1 Recombinant Protein Antigen
Species: Hu
Applications: AC


POT1 (protection of telomeres 1), a telomere regulator, is a single-stranded telomeric DNA-binding protein that controls telomerase-mediated telomere elongation. Telomere maintenance is required for protection against changes in telomere length, which has been implicated in ageing and certain cancers. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Excessive transcriptional expression of POT1 has been associated with stomach cancers.


Entrez Human
Uniprot Human
Product By Gene ID 25913
Alternate Names
  • protection of telomeres protein 1
  • POT1-like telomere end-binding protein
  • POT1 protection of telomeres 1 homolog
  • hPot1
  • DKFZp586D211
  • HPOT1
  • protection of telomeres 1 homolog (S. pombe)

Research Areas for POT1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Chromatin Research
DNA replication, Transcription, Translation and Splicing

PTMs for POT1

Learn more about PTMs related to POT1.


Bioinformatics Tool for POT1

Discover related pathways, diseases and genes to POT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related POT1 Blog Posts

Check out the latest blog posts on POT1.
Application Highlight: Recent uses of TERF2 in immunofluorescence (IF)
Telomeres are a region of repeat nucleotide sequences located at the end of chromosomes to protect our DNA from becoming damaged via end-to-end fusion.  TERF2, or telomeric-repeat binding factor 2, is important for telomere integrity and aids in th...    Read more.
Read more POT1 related blogs.