POT1 Products

Antibodies
POT1 Antibody
POT1 Antibody
NB100-56429
Species: Hu
Applications: WB, GS
Host: Rabbit Polyclonal
POT1 Antibody (688923)
POT1 Antibody (688923)
MAB5299
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Lysates
POT1 Overexpression Lysate (N ...
POT1 Overexpression Lysate (Native)
NBL1-14614
Applications: WB
Proteins
Recombinant Human POT1 Protei ...
Recombinant Human POT1 Protein
H00025913-Q01
Species: Hu
Applications: WB, ELISA, PA
POT1 Blocking Peptide
POT1 Blocking Peptide
NB500-176PEP
Species: Hu
POT1 Recombinant Protein Anti ...
POT1 Recombinant Protein Antigen
NBP2-57891PEP
Species: Hu
Applications: AC
RNAi
POT1 RNAi
POT1 RNAi
H00025913-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

POT1 (protection of telomeres 1), a telomere regulator, is a single-stranded telomeric DNA-binding protein that controls telomerase-mediated telomere elongation. Telomere maintenance is required for protection against changes in telomere length, which has been implicated in ageing and certain cancers. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Excessive transcriptional expression of POT1 has been associated with stomach cancers.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 25913
Alternate Names
  • protection of telomeres protein 1
  • POT1-like telomere end-binding protein
  • POT1 protection of telomeres 1 homolog
  • hPot1
  • DKFZp586D211
  • HPOT1
  • protection of telomeres 1 homolog (S. pombe)

Research Areas for POT1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Chromatin Research
DNA replication, Transcription, Translation and Splicing

PTMs for POT1

Learn more about PTMs related to POT1.

Phosphorylation
Methylation
Ubiquitination

Bioinformatics Tool for POT1

Discover related pathways, diseases and genes to POT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related POT1 Blog Posts

Check out the latest blog posts on POT1.
Application Highlight: Recent uses of TERF2 in immunofluorescence (IF)
Telomeres are a region of repeat nucleotide sequences located at the end of chromosomes to protect our DNA from becoming damaged via end-to-end fusion.  TERF2, or telomeric-repeat binding factor 2, is important for telomere integrity and aids in th...    Read more.
Read more POT1 related blogs.