p53 Products

p53 Antibody [Unconjugated]
p53 Antibody [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IP, ChIP, ICC/IF, KO
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Antibody Pairs
p53 Antibody Pair [HRP]
p53 Antibody Pair [HRP]
Species: Pm-Cm
Applications: ELISA, S-ELISA
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Human Total p53 DuoSet IC ELI ...
Human Total p53 DuoSet IC ELISA, 2...
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Human Phospho-p53 (S15) DuoSe ...
Human Phospho-p53 (S15) DuoSet IC ...
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Human p53 ELISA Kit (Chemilum ...
Human p53 ELISA Kit (Chemiluminesc...
Species: Hu
Applications: ELISA
p53 Transcription Factor Assa ...
p53 Transcription Factor Assay Kit...
Applications: Func
p53 Overexpression Lysate
p53 Overexpression Lysate
Species: Hu
Applications: WB
p53 Overexpression Lysate
p53 Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human His6-FLAG-p ...
Recombinant Human His6-FLAG-p53 Pr...
Species: Hu
Formulation Catalog # Availability Price  
Recombinant Human His6-p53 Pr ...
Recombinant Human His6-p53 Protein...
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
p53 Recombinant Protein Antig ...
p53 Recombinant Protein Antigen
Species: Hu
Applications: AC


p53 is a stress-regulated transcription factor that was first identified as an SV40 large T antigen-binding protein. It plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. This antibody can be used for the specific detection of human p53 that is synthesized in the presence of p53 from other species.


Uniprot Human
Product By Gene ID 7157
Alternate Names
  • Antigen NY-CO-13
  • FLJ92943
  • LFS1TRP53
  • p53 tumor suppressor
  • p53
  • P53cellular tumor antigen p53
  • Phosphoprotein p53
  • transformation-related protein 53
  • tumor protein p53
  • Tumor suppressor p53

Bioinformatics Tool for p53

Discover related pathways, diseases and genes to p53. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related p53 Blog Posts

Check out the latest blog posts on p53.
The role of p53 in UV radiation DNA damage and subsequent tumorogenesis
p53, the protein product of the tp53 gene, is one of the most widely studied tumor suppressor proteins in cancer research.  p53 is unique in that it demonstrates both tumor suppressive and tumor progressive properties depending on whether it is fu...    Read more.
Pathway Highlight: Which caspase substrates contribute to the morphological features associated with apoptosis?
Apoptosis, or programmed cell death, is controlled by a caspase signal cascade that activates downstream signals to induce the morphological changes used to differentiate apoptosis from other forms of cell death.  Novus Biologicals offers a variet...    Read more.
The Link Between Base Excision Repair and Cancer Antibodies
Base excision repair (BER) is the most fundamental DNA repair mechanism, dealing with alterations arising in individual DNA bases during cellular metabolism. We at Novus Biologicals have a large BER antibody database, which has proven important in var...    Read more.
The Heat is On: Heat Shock Proteins and the Link to Cancer
Novus Biologicals offers an extensive antibody catalog targeting heat shock proteins (HSPs). A large protein group covering a number of families, the HSPs are functionally related by their dramatic upregulation in response to stress. Stress triggers m...    Read more.
Recent Developments in p53 Antibody Research
P53 is a stress-activated transcription factor, encoded by the TP53 gene. An important tumor suppressor, the protein mediates cellular growth and proliferation, regulating proteins involved in the stress-response. In p53 antibody studies, the protein ...    Read more.
S100A6: Playing Roles in Cancer, Apoptosis & Transcription Regulation
S100A6 antibodies detect a small calcium binding protein with 2 EF-hand structures and belongs to the S100 family. Calcium binding induces a conformational change of the protein which in turn permits its interaction with several target proteins. It is...    Read more.
Beclin 1: Regulator of Autophagy and Apoptosis
Beclin 1 is the mammalian orthologue of the yeast Apg6/Vps30 gene. Beclin 1 can complement the defect in autophagy present in apg6 yeast strains and stimulate autophagy when overexpressed in mammalian cells (1) and can bind to Bcl2, an important regul...    Read more.
No Monkey Business: APE1 is a Critical DNA Repair Enzyme
APE1 (aka. HAP1, /Ref-1 or APEX) the mammalian ortholog of Escherichia coli Xth is a multifunctional protein possessing both DNA repair and transcriptional regulatory activity. APE1 acts essentially as master regulator of controlling cellular response...    Read more.
p14 ARF is an Important Tumor Suppressor
The p14ARF (Alternative Reading Frame) tumor suppressor is a protein product of the alternative reading frame (ARF) of the human INK4a locus which regulates a series of cell cycle regulatory proteins to promote cell cycle arrest in response to abnorma...    Read more.
Nanog is a Master Controller of ES cell Pluripotency
Nanog, a homeodomain (HD) transcription factor, plays a critical role in the maintenance of embryonic stem (ES) cell self-renewal. Transcription regulator involved in inner cell mass and ES cell proliferation and self-renewal. Imposes pluripotency on ...    Read more.
PRMT6: One Function, Many Roles
Protein arginine methylation is a prevalent posttranslational modification in eukaryotic cells. It regulates RNA processing, trafficking and nascent pre-RNA metabolism, receptor-mediated signal transduction, and transcriptional activation processes. P...    Read more.
p73: An Important Tumor Suppressor Cousin of p53
p73 has been identified as a long-lost cousin of the p53 tumor suppressor protein. It has high homology with both p53 and with p63, a gene implicated in the maintenance of epithelial stem cells. The presence of significant homology between the DNA-bin...    Read more.
Killing two birds with one stone: Treating inflammation and cancer by inhibiting prolyl-4-hydroxylase-1
By Jamshed Arslan Pharm.D. The cell’s oxygen-sensing machinery comprises prolyl-4-hydroxylases (P4Hs 1-3, PHDs 1-3, or EGLN 1-3) and their canonical target hypoxia-inducible factors (HIFs). When oxygen levels ...    Read more.
Autophagy independent roles of the core ATG proteins
By Christina Towers, PhD. Autophagy and ATG ProteinsAutophagy is a nutrient recycling process that cells use to fuel metabolism, particularly in response to nutrient deprivation.  It is critical for removal of dam...    Read more.
Developmental regulator Daam2 promotes glial cell tumors by degrading Von Hippel-Lindau protein
By Jamshed Arslan Pharm.D. Glioblastoma is an aggressive type of cancer that forms from the star-shaped glial cells of the central nervous system, called astrocytes. Intriguingly, several genes linked to glioblasto...    Read more.
NOXA - a BH3-only protein balancing cell death decisions
Noxa is a BH3-only protein involved in regulating cell death decisions. Noxa is a primary p53-response gene and is upregulated in response to p53 overexpression or DNA damage. Noxa can also be induced by alternative mechanisms including through a ...    Read more.
ATM - detecting and responding to DNA damage
Ataxia telangiectasia mutated (ATM) is essential for the maintenance of genomic stability. ATM is a 370 kDa serine-threonine kinase that is constitutively expressed in various tissues. Although primarily nuclear, ATM is also found at lower levels ...    Read more.
p53 - Investigating an important tumor suppressor
p53 is a tumor suppressor that has a central role in regulating cell cycle arrest, DNA repair, and apoptosis. p53 is widely studied for its role in cancer and is mutated or altered in more than half of all cancers (1). This widespread role in tumor...    Read more.
MAPK8/JNK1 - A multifunctional kinase and drug target for cancer therapeutics
The c-Jun N-terminal kinase (JNK) family is a group of regulatory kinases with important functions in cell morphogenesis, inflammation, differentiation, and cell death (1). Aberrant activation of JNK family proteins in cancers has led to interest i...    Read more.
Read more p53 related blogs.