Hu, Mu, PmApplications:
WB, Flow, Flow-IC, ICC/IF, IHC, IHC-Fr, IHC-P, IPHost:
WB, ICC/IF, IHC, IHC-P, IPHost:
WB, IHC, IHC-Fr, IHC-P, IPHost:
NOD2 (nucleotide-binding oligomerization domain containing 2) is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB. It also acts as an intracellular receptor for bacterial lipopolysaccharides and contributes to inflammatory bowel disease (IBD) and Crohn's disease.
|Product By Gene ID
- Caspase recruitment domain-containing protein 15
- nucleotide-binding oligomerization domain-containing protein 2
- caspase recruitment domain family, member 15
- nucleotide-binding oligomerization domain, leucine rich repeat and CARD domaincontaining 2
- nucleotide-binding oligomerization domain 2
- NOD-like receptor C2
- IBD1NLR family, CARD domain containing 2
- CARD15caspase recruitment domain protein 15
- Inflammatory bowel disease protein 1
- nucleotide-binding oligomerization domain containing 2
Bioinformatics Tool for NOD2
Discover related pathways, diseases and genes to NOD2. Need help? Read the Bioinformatics Tool Guide
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Related NOD2 Blog Posts
Check out the latest blog posts on NOD2.
Read more NOD2 related blogs.
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