Hu, Mu, PmApplications:
WB, Flow, Flow-IC, ICC/IF, IHC, IHC-Fr, IHC-P, IPHost:
WB, ICC/IF, IHC, IHC-P, IPHost:
WB, IHC, IHC-Fr, IHC-P, IPHost:
Applications: WB, IHC, IHC-Fr, IHC-P, IP
NOD2 (nucleotide-binding oligomerization domain containing 2) is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB. It also acts as an intracellular receptor for bacterial lipopolysaccharides and contributes to inflammatory bowel disease (IBD) and Crohn's disease.
|Product By Gene ID
- Caspase recruitment domain-containing protein 15
- nucleotide-binding oligomerization domain-containing protein 2
- caspase recruitment domain family, member 15
- nucleotide-binding oligomerization domain, leucine rich repeat and CARD domaincontaining 2
- nucleotide-binding oligomerization domain 2
- NOD-like receptor C2
- IBD1NLR family, CARD domain containing 2
- CARD15caspase recruitment domain protein 15
- Inflammatory bowel disease protein 1
- nucleotide-binding oligomerization domain containing 2
Bioinformatics Tool for NOD2
Discover related pathways, diseases and genes to NOD2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Related NOD2 Blog Posts
Check out the latest blog posts on NOD2.
Read more NOD2 related blogs.
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