Insulin Products

Rat Insulin ELISA Kit (Colori ...
Rat Insulin ELISA Kit (Colorimetric)
Species: Rt
Applications: ELISA
Mouse Insulin ELISA Kit (Colo ...
Mouse Insulin ELISA Kit (Colorimet...
Species: Mu
Applications: ELISA
Monkey Insulin ELISA Kit (Col ...
Monkey Insulin ELISA Kit (Colorime...
Species: Mk
Applications: ELISA
Insulin Knockout HeLa Cell Ly ...
Insulin Knockout HeLa Cell Lysate
Species: Hu
Applications: WB
Insulin Overexpression Lysate ...
Insulin Overexpression Lysate (Nat...
Species: Hu
Applications: WB
Recombinant Human Insulin Pro ...
Recombinant Human Insulin Protein
Species: Hu
Applications: PAGE, Bioactivity
Insulin Recombinant Protein A ...
Insulin Recombinant Protein Antigen
Species: Hu
Applications: AC
Recombinant Human Insulin Pro ...
Recombinant Human Insulin Protein
Species: Hu
Applications: Bioactivity


After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. (provided by RefSeq)


Entrez Human
Uniprot Human
Product By Gene ID 3630
Alternate Names
  • IRDN
  • proinsulin
  • ILPR
  • MODY10
  • IDDM2
  • insulin

Research Areas for Insulin

Find related products by research area and learn more about each of the different research areas below.

Diabetes Research
Immune System Diseases
Stem Cell Markers

Bioinformatics Tool for Insulin

Discover related pathways, diseases and genes to Insulin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related Insulin Blog Posts

Check out the latest blog posts on Insulin.
Eat responsibly: Epigenetic downregulation of Ankrd26 gene by long-term high-fat intake promotes obesity and inflammation
By Jamshed Arslan Pharm.D. White adipose tissue (WAT) represents the primary site to store energy in humans. WAT’s endocrine regulation of energy balance is controlled by nutritional status, exercise, and hormones l...    Read more.
Application Focus: New Methods for iPSC Differentiation, Inducing a Mammary Fate
Discovery of the Key to PluripotencyInduced pluripotent stem cells (iPSCs) may be generated from a wide range of fully differentiated cells, and under optimal conditions may be prompted to differentiate into virtu...    Read more.
The effects of curcumin on IKB Alpha and the NFkB signaling pathway
The IKK complex, or inhibitor of NFkB kinase, is composed of IKK alpha and IKK beta.  These kinases are at the core of the NFkB signaling cascade.  The NFkB family is made up of transcription factors that are kept inactive in the cytoplasm through...    Read more.
AMPK Alpha 1 and lipid metabolism of adipocytes
AMP-activated protein kinase (AMPK) is best known as a sensor of oxidative stress.  AMPK is activated by increased intracellular AMP levels, which are a result of alterations in cellular metabolism from causes such as hypoxia, changes in ATP, sene...    Read more.
ChREBP, a glucose sensitive transcription factor with role in glucose-lipids homeostasis and cancer
ChREBP (carbohydrate response element-binding protein) is a glucose responsive basic helix-loop-helix/leucine zipper (bHLH/LZ) transcription factor that binds MLX and then carbohydrate response element /ChoRE for the induction of genes involved in...    Read more.
Ghrelin: Targeting the Hunger Hormone to Combat Obesity and Type 2 Diabetes
As the hormone ghrelin is linked to appetite and weight gain, as well as impaired glucose-induced insulin secretion, there is considerable interest in this peptide as a potential drug target. Although the overall lack of success in this field has been...    Read more.
Novus Adiponectin Reagents Help to Progress Obesity & Diabetes Research
Adiponectin is most well-known for its role in glucose metabolism and fatty acid breakdown. Adiponectin is secreted solely by adipose tissue, and a person with a higher percentage of body fat will express lower levels of Adiponectin. When higher level...    Read more.
Signalling Advances in Adiponectin Antibody Research
Adiponectin is an adipocytokine protein that positively regulates metabolism of lipids and glucose by suppressing glucose production from the liver, stimulating insulin sensitivity, and increasing the rate of fatty acid oxidation and glucose uptake. I...    Read more.
Read more Insulin related blogs.