HGF Products

Antibodies
HGF Antibody [Unconjugated]
HGF Antibody [Unconjugated]
AF-294-NA
Species: Hu
Applications: WB, IHC, B/N
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
HGF Antibody (24612) [Unconju ...
HGF Antibody (24612) [Unconjugated]
MAB294
Species: Hu
Applications: WB, IHC, B/N
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
HGF Antibody [Unconjugated]
HGF Antibody [Unconjugated]
AF2207
Species: Mu
Applications: WB, IHC, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
ELISA Kits
Mouse/Rat HGF Quantikine ELIS ...
Mouse/Rat HGF Quantikine ELISA Kit
MHG00
Species: Mu, Rt
Applications: ELISA
Human HGF DuoSet ELISA, 15 Pl ...
Human HGF DuoSet ELISA, 15 Plate
DY294
Species: Hu
Applications: ELISA
Mouse HGF DuoSet ELISA, 15 Pl ...
Mouse HGF DuoSet ELISA, 15 Plate
DY2207
Species: Mu
Applications: ELISA
Lysates
HGF Overexpression Lysate
HGF Overexpression Lysate
NBL1-11527
Species: Hu
Applications: WB
Proteins
Recombinant Human HGF Protein ...
Recombinant Human HGF Protein
294-HG
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse HGF Protein ...
Recombinant Mouse HGF Protein
2207-HG
Species: Mu
Applications: Binding Activity, Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human HGF (NS0-ex ...
Recombinant Human HGF (NS0-express...
294-HGN
Species: Hu
Applications: Bioactivity

Description

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq]

Bioinformatics

Entrez Mouse
Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Alternate Names
  • deafness, autosomal recessive 39
  • DFNB39
  • EC 3.4.21
  • EC 3.4.21.7
  • fibroblast-derived tumor cytotoxic factor
  • F-TCF
  • hepatocyte growth factor (hepapoietin A; scatter factor)
  • Hepatopoeitin-A
  • HGFB
  • HPTAhepatocyte growth factor
  • lung fibroblast-derived mitogen
  • Scatter factor
  • SFhepatopoeitin-A

Research Areas for HGF

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication