HGF Products

Antibodies
HGF Antibody [Unconjugated]
HGF Antibody [Unconjugated]
AF-294-NA
Species: Hu
Applications: WB, IHC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
HGF Antibody
HGF Antibody
AF2207
Species: Mu
Applications: WB, IHC, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
HGF Antibody (24612) [Unconju ...
HGF Antibody (24612) [Unconjugated]
MAB294
Species: Hu
Applications: WB, Neut
Host: Mouse Monoclonal
ELISA Kits
Human HGF ELISA Kit (Colorime ...
Human HGF ELISA Kit (Colorimetric)
KA0343
Species: Hu
Applications: ELISA
Mouse HGF ELISA Kit (Colorime ...
Mouse HGF ELISA Kit (Colorimetric)
KA1785
Species: Mu
Applications: ELISA
Mouse HGF ELISA Kit (Colorime ...
Mouse HGF ELISA Kit (Colorimetric)
KA1786
Species: Mu
Applications: ELISA
Lysates
HGF Overexpression Lysate (Na ...
HGF Overexpression Lysate (Native)
NBL1-11527
Applications: WB
HGF Overexpression Lysate (De ...
HGF Overexpression Lysate (Denatured)
H00003082-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human HGF Protein ...
Recombinant Human HGF Protein
294-HG
Species: Hu
Applications: BA
Recombinant Mouse HGF Protein ...
Recombinant Mouse HGF Protein
2207-HG
Species: Mu
Applications: BA, Bind
Human HGF Biologically Active ...
Human HGF Biologically Active Protein
NBP2-35338
Species: Hu
Applications: Func, PAGE
RNAi
HGF RNAi
HGF RNAi
H00003082-R02
Species: Hu
Applications: RNAi, RNAi SP
HGF RNAi
HGF RNAi
H00003082-R05
Species: Hu
Applications: RNAi, RNAi SP
HGF RNAi
HGF RNAi
H00003082-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq]

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 3082
Alternate Names
  • EC 3.4.21.7
  • EC 3.4.21
  • deafness, autosomal recessive 39
  • Scatter factor
  • DFNB39
  • Hepatopoeitin-A
  • HGFB
  • lung fibroblast-derived mitogen
  • F-TCF
  • SFhepatopoeitin-A
  • HPTAhepatocyte growth factor
  • fibroblast-derived tumor cytotoxic factor
  • hepatocyte growth factor (hepapoietin A; scatter factor)

Research Areas for HGF

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication

Bioinformatics Tool for HGF

Discover related pathways, diseases and genes to HGF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related HGF Blog Posts

Check out the latest blog posts on HGF.
The role of HIF-2 alpha in the progression and therapy of clear cell renal cell carcinoma
HIF-2 alpha, also known as hypoxia-inducible factor 2, endothelial PAS domain protein-1, and member of PAS superfamily 2 is part of the HIF family of proteins.  The HIF family is composed of HIF-1, HIF-2 and HIF-3, where HIF-2 is a dimeric protein...    Read more.
VEGFR-2 - A highly active kinase
VEGFR-2 is a family member of the vascular endothelial growth factor (VEGF) family of membrane receptor tyrosine kinases. It is a key regulator of the process of angiogenesis that takes place during fundamental developmental processes such as embry...    Read more.
Read more HGF related blogs.