G-CSF Products

Description

Granulocyte Colony-Stimulating Factor (G-CSF , filgrastim, pegfilgrastim or lenograstim) is a hematopoietic growth factor that stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/granulocyte lineage, in a dose-dependent manner. It is produced by a variety of cells including macrophages, monocytes, fibroblasts, endothelial cells and bone marrow stroma in response to specific stimulation by f.ex. endotoxin, TNF-alpha and IFN-gamma. Clinical applications of G-CSF include treatment of leukopenia following cancer therapy and bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is a 18.7 kDa glycoprotein containing 174 amino acid residues.

Bioinformatics

Entrez	12985 Mouse 1440 Human
Uniprot	NM_000759 Human NM_172219 Human NM_172220 Human NP_000750 Human NP_000750.1 Human NP_757373 Human P09919 Human P09920 Mouse
Product By Gene ID	1440
Alternate Names	C17orf33 chromosome 17 open reading frame 33 colony stimulating factor 3 (granulocyte) CSF3OS filgrastim Filgrastim G-CSF GCSFlenograstim granulocyte colony-stimulating factor Lenograstim MGC45931 Pluripoietin pluripoietin

Research Areas for G-CSF

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins
Cell Cycle and Replication
Cytokine Research