DARPP-32 Products

Antibodies
DARPP-32 [p Thr75] Antibody
DARPP-32 [p Thr75] Antibody
NB300-234
Species: Hu, Mu, Rt, Bovine, Canine, Chicken, Primate
Applications: WB
Host: Rabbit Polyclonal
DARPP-32 Antibody
DARPP-32 Antibody
Species: Hu, Mu, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DARPP-32 [p Thr34] Antibody
DARPP-32 [p Thr34] Antibody
NB300-224
Species: Mu, Rt, Bovine, Canine, Chicken, Human, Primate
Applications: WB, IHC
Host: Rabbit Polyclonal
Lysates
DARPP-32 Overexpression Lysat ...
DARPP-32 Overexpression Lysate (De...
H00084152-T01
Species: Hu
Applications: WB
DARPP-32 Overexpression Lysat ...
DARPP-32 Overexpression Lysate (Na...
NBL1-14679
Applications: WB
DARPP-32 Overexpression Lysat ...
DARPP-32 Overexpression Lysate (Na...
NBL1-14680
Applications: WB
Proteins
DARPP-32 Recombinant Protein
DARPP-32 Recombinant Protein
H00084152-P01
Species: Hu
Applications: WB, ELISA, PA
DARPP-32 Recombinant Protein ...
DARPP-32 Recombinant Protein Antigen
NBP2-33534PEP
Species: Hu
Applications: AC
DARPP-32 Recombinant Protein ...
DARPP-32 Recombinant Protein Antigen
NBP2-38908PEP
Species: Hu
Applications: AC
RNAi
DARPP-32 RNAi
DARPP-32 RNAi
H00084152-R02
Species: Hu
Applications: RNAi, RNAi SP
DARPP-32 RNAi
DARPP-32 RNAi
H00084152-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

DARPP-32, a dopamine (DA) and cAMP-regulated ~32k phosphoprotein, is associated with dopaminoceptive neurons bearing D-1 receptors in the basal ganglia. The protein inhibits protein phosphatase I when it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA. Phosphorylation of DARPP is thought to play a critical role in the regulation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Rat
Product By Gene ID 84152
Alternate Names
  • regulatory (inhibitor) subunit 1B (dopamine and cAMPregulated phosphoprotein, DARPP-32)
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B

Research Areas for DARPP-32

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Neuronal Cell Markers
Neuroscience
Neurotransmission
Phospho-Specific
Protein Phosphatase
Signal Transduction

PTMs for DARPP-32

Learn more about PTMs related to DARPP-32.

Phosphorylation
Dephosphorylation
Acetylation
Deacetylation
Cleavage
Palmitoylation

Bioinformatics Tool for DARPP-32

Discover related pathways, diseases and genes to DARPP-32. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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