DARPP-32 Products

Antibodies
DARPP-32 Antibody (SU0329)
DARPP-32 Antibody (SU0329)
NBP2-67462
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
DARPP-32 Antibody
DARPP-32 Antibody
AF6259
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
DARPP-32 Antibody (375604) [U ...
DARPP-32 Antibody (375604) [Unconj...
MAB4230
Species: Mu, Rt
Applications: WB, IHC
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
Lysates
DARPP-32 Overexpression Lysat ...
DARPP-32 Overexpression Lysate
NBL1-14679
Species: Hu
Applications: WB
DARPP-32 Overexpression Lysat ...
DARPP-32 Overexpression Lysate
NBL1-14680
Species: Hu
Applications: WB
Proteins
Recombinant Human DARPP-32 Pr ...
Recombinant Human DARPP-32 Protein
H00084152-P01
Species: Hu
Applications: WB, ELISA, PA, AP
DARPP-32 Recombinant Protein ...
DARPP-32 Recombinant Protein Antigen
NBP2-38908PEP
Species: Hu
Applications: AC
DARPP-32 Recombinant Protein ...
DARPP-32 Recombinant Protein Antigen
NBP2-33534PEP
Species: Hu
Applications: AC

Description

DARPP-32, a dopamine (DA) and cAMP-regulated ~32k phosphoprotein, is associated with dopaminoceptive neurons bearing D-1 receptors in the basal ganglia. The protein inhibits protein phosphatase I when it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA. Phosphorylation of DARPP is thought to play a critical role in the regulation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Rat
Product By Gene ID 84152
Alternate Names
  • regulatory (inhibitor) subunit 1B (dopamine and cAMPregulated phosphoprotein, DARPP-32)
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B

Research Areas for DARPP-32

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Neuronal Cell Markers
Neuroscience
Neurotransmission
Phospho-Specific
Protein Phosphatase
Signal Transduction

PTMs for DARPP-32

Learn more about PTMs related to DARPP-32.

Phosphorylation
Dephosphorylation
Acetylation
Deacetylation
Cleavage
Palmitoylation

Bioinformatics Tool for DARPP-32

Discover related pathways, diseases and genes to DARPP-32. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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