CXCR2/IL-8RB Products

Description

Chemokine (Chemoattractant Cytokines) are small peptides that are potent activators and chemo-attractants for leukocyte subpopulations and other non-hemopoietic cells. Chemokine receptors (CXCR) belong to the super-family of G protein-coupled receptors (GPCR), which regulate the trafficking and activation of leukocytes, and operate as co-receptors in the entry of HIV-1 and proliferation and migration of immature neurons, glia and their precursors. Furthermore, chemokine receptors participate in the etiology and progression of various brain disorders, including AIDS dementia, neuro-inflammatory disease and neuroplasia, making them important potential therapeutic targets in these cases several subtypes of CXCR have been characterized. Activation of na

Bioinformatics

Entrez	29385 Rat 3579 Human
Uniprot	NM_001557 Human NP_001548 Human NP_001548.1 Human P25025 Human P35343 Mouse
Product By Gene ID	3579
Alternate Names	CD182 antigen CDw128b chemokine (C-X-C motif) receptor 2 chemokine (CXC) receptor 2 C-X-C chemokine receptor type 2 CXCR2 gene for IL8 receptor type B CXC-R2 CXCR-2 GRO/MGSA receptor High affinity interleukin-8 receptor B IL-8 receptor type 2 IL-8R B IL8R2 IL8RA interleukin 8 receptor B interleukin 8 receptor type 2 interleukin-8 receptor type B

Research Areas for CXCR2/IL-8RB

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cytokine Research
GPCR
Immunology
Innate Immunity