CXCL12/SDF-1 Products

Antibodies
CXCL12/SDF-1 Antibody (79014) ...
CXCL12/SDF-1 Antibody (79014) [Unc...
MAB310
Species: Hu, Mu
Applications: Neut
Host: Mouse Monoclonal
CXCL12/SDF-1 Antibody [Unconj ...
CXCL12/SDF-1 Antibody [Unconjugated]
AF-310-NA
Species: Hu
Applications: WB, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
CXCL12/SDF-1 ELISA Kit [Bioti ...
CXCL12/SDF-1 ELISA Kit [Biotin]
KA1876
Species: Hu
Lysates
CXCL12/SDF-1 Overexpression L ...
CXCL12/SDF-1 Overexpression Lysate...
NBP2-10687
Applications: WB
CXCL12/SDF-1 Overexpression L ...
CXCL12/SDF-1 Overexpression Lysate...
NBL1-09623
Applications: WB
Proteins
CXCL12/SDF-1 Recombinant Prot ...
CXCL12/SDF-1 Recombinant Protein
NBC1-27995
Species: Hu
Applications: PAGE
CXCL12/SDF-1 Recombinant Prot ...
CXCL12/SDF-1 Recombinant Protein
NBP2-52161
Species: Mu
Applications: PAGE
CXCL12/SDF-1 Recombinant Prot ...
CXCL12/SDF-1 Recombinant Protein
NBP1-99858
Species: Hu
RNAi
CXCL12/SDF-1 RNAi
CXCL12/SDF-1 RNAi
H00006387-R02
Species: Hu
CXCL12/SDF-1 RNAi
CXCL12/SDF-1 RNAi
H00006387-R03
Species: Hu
CXCL12/SDF-1 RNAi
CXCL12/SDF-1 RNAi
H00006387-R01
Species: Hu

Description

The C-X-C or alpha chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell-derived factor-1, or SDF-1. SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemoattractant for T cells and monocytes, but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven-pass, transmembrane domain proteins which include IL-8RA, IL-8RB and fusin (also designated LESTR or CXCR-4). Fusin is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. Fusin has been identified as the major co-receptor for T-tropic HIV-1, and SDF-1 has been shown to inhibit HIV-1 infection. Six human SDF-1 isoforms exist due to alternative splicing of CXCL12, the gene encoding SDF-1. Three isoforms are known for mouse and rat.

Bioinformatics

Entrez Human
Mouse
Feline
Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Feline
Product By Gene ID 6387
Alternate Names
  • hSDF-1
  • SDF1A
  • hIRH
  • IRH
  • C-X-C motif chemokine 12
  • Pre-B cell growth-stimulating factor
  • SDF-1
  • Intercrine reduced in hepatomas
  • TLSF
  • stromal cell-derived factor 1
  • TLSF-b
  • TPAR1
  • TLSF-a
  • SCYB12
  • SDF1SDF-1b
  • PBSFSDF-1a
  • SDF1B
  • chemokine (C-X-C motif) ligand 12

Research Areas for CXCL12/SDF-1

Find related products by research area and learn more about each of the different research areas below.

Growth and Development
Neuronal Cell Markers

Bioinformatics Tool for CXCL12/SDF-1

Discover related pathways, diseases and genes to CXCL12/SDF-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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