Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IP, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Description
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B), also known as BubR1, is a kinase involved in spindle checkpoint function. BUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early. BUBR1 has been detected in human cancers. BubR-1 localizes to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation.
BubR1 antibodies are useful tools for cancer research and cell division studies.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
701 |
| Alternate Names |
- Bub1A
- BUBR1budding uninhibited by benzimidazoles 1 (yeast homolog), beta
- budding uninhibited by benzimidazoles 1 homolog beta (yeast)
- EC 2.7.11.1
- hBUBR1
- MAD3/BUB1-related protein kinase
- MAD3LBUB1beta
- Mitotic checkpoint kinase MAD3L
- Protein SSK1
- SSK1mitotic checkpoint serine/threonine-protein kinase BUB1 beta
|
