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BubR1 Products

Antibodies
BubR1 Antibody (2G5) - Azide ...
BubR1 Antibody (2G5) - Azide and B...
H00000701-M02
Species: Hu
Applications: WB, ELISA, Func, ICC/IF, IHC, Mycoplasma
Host: Mouse Monoclonal
Lysates
BubR1 Overexpression Lysate
BubR1 Overexpression Lysate
NBL1-08057
Species: Hu
Applications: WB
Proteins
Recombinant Human BubR1 GST ( ...
Recombinant Human BubR1 GST (N-Ter...
H00000701-P01
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP

Description

Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B), also known as BubR1, is a kinase involved in spindle checkpoint function. BUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early. BUBR1 has been detected in human cancers. BubR-1 localizes to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation.

BubR1 antibodies are useful tools for cancer research and cell division studies.

Bioinformatics

Product By Gene ID 701
Alternate Names
  • Bub1A
  • BUBR1budding uninhibited by benzimidazoles 1 (yeast homolog), beta
  • budding uninhibited by benzimidazoles 1 homolog beta (yeast)
  • EC 2.7.11.1
  • hBUBR1
  • MAD3/BUB1-related protein kinase
  • MAD3LBUB1beta
  • Mitotic checkpoint kinase MAD3L
  • Protein SSK1
  • SSK1mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Research Areas for BubR1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cell Cycle and Replication
Chromatin Research
Core ESC-Like Genes
DNA Repair
Mitotic Regulators
Stem Cell Markers