CiteAb 2017 Antibody Awards: The Lifetime Achievement Award Recipient Karen Padgett

The CiteAb Lifetime Achievement Award recognizes and promotes an individual who has made an outstanding contribution to the research antibody industry over a sustained period of time.

Immunophenotyping: A Process of Identifying Cells and Cell Markers

Flow cytometry is one of the powerful tools for the investigators in immunological research involved in studying various immune cells. One of the main advantages of this technique is that is capable of multi-parameter measurements that can be accomplished on a single-cell basis. As a result of the advances in the flow cytometry researchers can now decrypt the phenotypes of several cell subsets in ways that were not possible using traditional assays, such as Western/immunoblotting, microarrays and enzyme-linked immunosorbent assays.

Perforin a Protective Serial Killer

Secretory granule-mediated cell death is one of the the key mechanisms for elimination of virus-infected and transformed target cells by cytotoxic lymphocytes.

New Research Takes the "Gag" Off to Reveal HIV Secrets

Antibody studies into the human immunodeficiency virus (HIV) centre around Gag, a highly complex polyprotein that has so far defied attempts to unravel its complex and varied modes of action. Now, a team from the NIST Center for Neutron Research have revealed a new model which has allowed the protein to be studied in far more clarity. The hope with antibody suppliers is that it will pave the way to understanding many more large, unfathomable proteins.

NER, BER, HR and Other DNA Repair Pathways

A large number of antibody assays are devoted to the study of nuclear excision repair (NER) proteins. However, there are a number of other DNA repair pathways, many of which are instigated by NER and share the same proteins. DNA repair antibodies are widely used in cancer research, and Novus Biologicals offers an extensive selection of thoroughly validated, high-quality DNA repair and cancer related antibodies.

How New Oval Stem Cell Marker Antibodies Will Benefit Hepatic Research

A large number of antibody suppliers supply conjugated and non-conjugated marker antibodies, targeted at specific stem cell populations. Until recently the number of oval stem cell markers was extremely limited. However, we at Novus Biologicals have succeeded in developing a new line of monoclonal antibodies specifically targeted to the murine oval cell response. These have just been added to our stem cell antibody database.

Antibody Research into Rare Tumours could Lead to Cutting-Edge Cancer Treatments

We at Novus Biologicals have a vast number of products in our antibody catalogue, targeted at cancer research. They cover areas as diverse as apoptosis and cell signalling pathways, and antibodies include those derived from a number of tumour cell lines.

Bestrophin Research Reveals Potential Target for Glaucoma Therapy

The Bestrophin 1 to 4 group of proteins are membrane-bound globulins, encoded by the BEST genes 1 to 4. We at Novus Biologicals have a range of products for Best research on our antibody database; mainly targeted to Best-1.

Mutations in CHD7 Provide Link Between CHARGE syndrome and Cancer Cell Metastasis

Antibody studies into human CHARGE syndrome have shown mutated CHD7 plays a major role in its development. CHARGE originates in neural crest cells (NCCs) during early embryonic development. It leads to a number of birth defects including craniofacial, heart, brain, urogenital, hearing and growth defects. New research conducted by Wysocka et al, of the Stamford University School of Medicine, indicates a connection with tumour development in adults.

City Gym Helps Sheffield University in FTO Fat Gene Research

The recently discovered FTO (Fat mass and obesity orientated) gene is of great interest to antibody research groups, throwing clearer insight into the reasons why some people have difficulty losing weight, even when following a healthy lifestyle.