Western Blot: Liprin alpha 1 Antibody [21720002] - Samples: Lane 1, Marker [kDa]: 250, 130, 95, 72, 55, 36, 28, 17, 11 Lane 2, RT-4 Lane 3, U-251MG sp Lane 4, Human Plasma Lane 5, Liver Lane 6, Tonsil , Target weight ...read more
Immunohistochemistry: Liprin alpha 1 Antibody [21720002] - Most of the normal tissues displayed moderate cytoplasmic positivity which was occasionally accompanied with nuclear staining. Strong cytoplasmic staining was ...read more
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified
Notes
Manufactured by SDIX's proprietary Genomic Antibody Technology. GAT FAQs.
Alternate Names for Liprin alpha 1 Antibody
FLJ42630
FLJ43474
LAR-interacting protein 1
LIP.1
LIP-1
LIP1FLJ41337
LIPRIN
Liprin-alpha1
liprin-alpha-1
MGC26800
Protein tyrosine phosphatase receptor type f polypeptide-interacting proteinalpha-1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interactingprotein (liprin), alpha 1
PTPRF-interacting protein alpha-1
Background
Liprin alpha 1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane. possibly regulating their interaction with the extracellular environment and their association with substrates.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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