Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv
Applications: WB, Simple Western, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC, KO, Mycoplasma
Host: Mouse Monoclonal
Species: Hu
Applications: PAGE
Species: Rt
Applications: PAGE
Species: Hu
Applications: AC
Description
Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role both in signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Whereas profilin I appears to be highly expressed in most tissues except for skeletal muscle, profilin II is predominantly expressed in brain and at lower levels. It is also in expressed in skeletal muscle, the uterus and kidneys. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.
Bioinformatics
| Product By Gene ID |
5216 |
| Alternate Names |
- PFN1
- PROF1
- Profilin 1
- Profilin I
- profilin-1
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Related Profilin 1 Blog Posts
Check out the latest blog posts on Profilin 1.
Profiling the Profilin 1 Antibody
Profilin-1, or Pfn-1, is a small actin-binding protein which plays an essential role controlling the growth of microfilaments. Profilin 1 and Profilin 2 have similar biochemical properties but are expressed in different tissues. The Profilin 1 antibod... Read more.
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Read more Profilin 1 related blogs.