UNC13B Antibody (584102) [DyLight 488]

• Reactivity: Hu
• Applications: IHC
• Clone: 584102
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

UNC13B Antibody (584102) [DyLight 488] Summary

• Immunogen: E. Coli-derived recombinant human UNC13B
  Asp418-Ser1591
  Accession # O14795
• Specificity: Detects human UNC13B in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) UNC13A and rhUNC13C is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: UNC13B
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for UNC13B Antibody (584102) [DyLight 488]

• hmunc13
• homolog of rat Munc13 (diacylglycerol-binding)
• MGC133279
• MGC133280
• MUNC13
• munc13-2
• MUNC13B
• protein unc-13 homolog B
• unc-13 homolog B (C. elegans)
• UNC13B
• Unc13h2
• unc-13-like (C. elegans)
• UNC13Unc13h2

Background

The UNC13B gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia i

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UNC13B