Snapin Antibody

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-SNAPAP )

Product Discontinued

Snapin Antibody Summary

• Immunogen: The immunogen for this antibody was a sequence from 31a.a. to 136a.a. from SNAPIN(a 136a.a. long protein)
• Localization: Golgi apparatus (By similarity).
• Specificity: SNAPIN
• Clonality: Polyclonal
• Host: Chicken
• Gene: SNAPIN
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:200-1:500
• Application Notes: Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
• Control:

  Snapin Overexpression Lysate

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for Snapin Antibody

• SNAP-25-binding protein
• SNAP25BP
• SNAPAP
• SNAPAPSNARE-associated protein Snapin
• SNAP-associated proteinSNARE associated protein snapin
• Snapin
• Synaptosomal-associated protein 25-binding protein

Background

SNAPIN is a component of the SNARE complex of proteins that is required for synaptic vesicle docking and fusion. It may modulate a step between vesicle priming, fusion and calcium dependent neurotransmitter release by potentiating the interaction of synaptotagmins with the SNAREs and the plasma membrane associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. It may also have a role in the mechanisms of SNARE mediated membrane fusion in non neuronal cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SNAPIN
• Entrez:
  • 23557(Human)
  • 20615(Mouse)
  • 295217(Rat)
• Uniprot:
  • O95295()