SLC39A12 Antibody

Western Blot: SLC39A12 Antibody [NBP2-75665] - Analysis of ZIP12 on HepG2 cell and rat lung tissue lysates using anti-ZIP12 antibody at 1/500 dilution.

Immunocytochemistry/Immunofluorescence: SLC39A12 Antibody [NBP2-75665] - Staining ZIP12 in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Immunohistochemistry-Paraffin: SLC39A12 Antibody [NBP2-75665] - Analysis of paraffin-embedded mouse eyeball tissue using anti-ZIP12 antibody. Counter stained with hematoxylin.

Immunocytochemistry/Immunofluorescence: SLC39A12 Antibody [NBP2-75665] - Staining ZIP12 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Immunohistochemistry-Paraffin: SLC39A12 Antibody [NBP2-75665] - Analysis of paraffin-embedded mouse liver tissue using anti-ZIP12 antibody. Counter stained with hematoxylin.

Immunohistochemistry-Paraffin: SLC39A12 Antibody [NBP2-75665] - Analysis of paraffin-embedded mouse brain tissue using anti-ZIP12 antibody. Counter stained with hematoxylin.

Product Discontinued

SLC39A12 Antibody Summary

• Immunogen: Synthetic peptide within Human SLC39A12 aa 685-691 / 691 (Extracellular). (SwissProt: Q504Y0 Human; SwissProt: Q5FWH7 Mouse)
• Localization: Membrane.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC39A12
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
• Theoretical MW: 70 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH7.4), 0.2% BSA, 50% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SLC39A12 Antibody

• bA570F3.1
• FLJ30499
• LIV-1 subfamily of ZIP zinc transporter 8
• LZT-Hs8
• MGC43205
• MGC51099
• solute carrier family 39 (metal ion transporter), member 12
• solute carrier family 39 (zinc transporter), member 12
• Solute carrier family 39 member 12
• zinc transporter ZIP12
• ZIP12
• ZIP-12
• Zrt- and Irt-like protein 12

Background

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipidmetabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson,2003 (PubMed 12659941)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SLC39A12 Antibody (NBP2-75665)(1)

Publication using NBP2-75665

• Arriaza K, Brito J, Siques P et al. Effects of Zinc on the Right Cardiovascular Circuit in Long-Term Hypobaric Hypoxia in Wistar Rats International journal of molecular sciences 2023-05-31 [PMID: 37298516] (WB, Rat)
  
  Details:
  1:200 WB dilution

Bioinformatics

• Gene Symbol: SLC39A12