RYBP/DEDAF Antibody

Product Discontinued

RYBP/DEDAF Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human RING1 and YY1 binding protein using the numbering given in entry NP_036366.3 (GeneID 23429).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RYBP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-10 mcg/mg lysate
• Application Notes: Works in IP, not recommended for WB

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for RYBP/DEDAF Antibody

• AAP1
• APAP-1
• Apoptin-associating protein 1
• Death effector domain-associated factor
• DEDAFYY1 and E4TF1-associated factor 1
• RING1 and YY1 binding protein
• RING1 and YY1-binding protein
• ring1 interactor RYBP
• YEAF1DED-associated factor
• YY1 and E4TF1 associated factor 1

Background

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. Several molecules including caspases and adaptor FADD contain DEDs. A novel protein that interacts with DED of caspase-8 and

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RYBP/DEDAF Antibody (NBP1-97742)(1)

Publication using NBP1-97742

• Holdt LM, Hoffmann S, Sass K et al. Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks. PLoS Genet 2013-07-01 [PMID: 23861667] (IP, Human)

Bioinformatics

• Gene Symbol: RYBP
• Uniprot:
  • Q8N488(Human)