RNF212 Antibody - BSA Free

Western Blot: RNF212 Antibody - BSA Free [NBP3-46707] - Human heart tissue were subjected to SDS PAGE followed by western blot with (RNF212 antibody) at dilution of 1:500

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

RNF212 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit RNF212 Antibody - BSA Free (NBP3-46707) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: ring finger protein 212. (Uniprot# Q495C1)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RNF212
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500-1:2000
• Theoretical MW: 22 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for RNF212 Antibody - BSA Free

• FLJ38841
• FLJ42587
• hypothetical protein LOC285498
• MGC120227
• MGC120228
• ring finger protein 212
• ZHP3

Background

RNF212, also known as Probable E3 SUMO-protein ligase RNF212, has 6 isoforms, a 297 amino acid isoform that is 33 kDa, a 123 amino acid isoform that is 14 kDa, a 192 amino acid isoform that is 22 kDa, a 280 amino acid isoform that is 31 kDa, a 232 amino acid isoform that is 26 kDa, and a 273 amino acid isoform that is 30 kDa. This protein may function as a ubiquitin ligase and may be involved in meiotic recombination, regulates crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes, localizes to recombination sites and stabilizes meiosis-specific recombination factors, may act as a SUMO E3 ligase that mediates sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites, and acts as a limiting factor for crossover designation and/or reinforcement.RNF212 protein is being studied for its involvement in recombination rate qtl 1 disorder. Little is currently known about this protein interactions with other proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RNF212