Relaxin R2/LGR8 Antibody

Immunohistochemistry-Paraffin: Relaxin R2/LGR8 Antibody [NLS4751] - Skin, Malignant Melanoma

Immunohistochemistry-Paraffin: Relaxin R2/LGR8 Antibody [NLS4751] - Analysis of anti-RXFP2 / LGR8 antibody with human uterus.

Immunohistochemistry-Paraffin: Relaxin R2/LGR8 Antibody [NLS4751] - Analysis of anti-RXFP2 / LGR8 antibody with human brain, glioblastoma.

Immunohistochemistry-Paraffin: Relaxin R2/LGR8 Antibody [NLS4751] - Anti-RXFP2 / LGR8 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: Relaxin R2/LGR8 Antibody [NLS4751] - Breast, carcinoma

Product Discontinued

Relaxin R2/LGR8 Antibody Summary

• Immunogen: Synthetic 17 amino acid peptide from 2nd extracellular domain of human RXFP2.
• Localization: Cell Membrane
• Specificity: Human RXFP2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except RXFP1 (53%).
• Predicted Species: Equine (94%), Monkey (94%), Bat (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RXFP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 18 - 72 ug/ml
• Control:

  Relaxin R2/LGR8 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (94%), Marmoset (94%), Elephant (94%), Panda (94%), Canine (88%), Porcine (88%), Bovine (82%), Rabbit (82%), Platypus (82%), Xenopus (82%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Relaxin R2/LGR8 Antibody

• G protein coupled receptor affecting testicular descent
• Gpr106
• GPR106G-protein coupled receptor 106
• Great
• GREATRelaxin family peptide receptor 2
• INSL3R
• leucine-rich repeat-containing G protein-coupled receptor 8
• Leucine-rich repeat-containing G-protein coupled receptor 8
• Lgr8
• LGR8.1
• LGR8G-protein coupled receptor affecting testicular descent
• Relaxin R2
• relaxin receptor 2
• relaxin/insulin-like family peptide receptor 2
• RelaxinR2
• RLN2R
• Rxfp2
• RXFPR2

Background

LGR8 is a member of the Relaxin Receptor subfamily. LGR8 has been shown to be important for testis descent. LGR8 has been reported in blood, bone marrow, brain, kidney, muscle, testis, thyroid, and uterus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Relaxin R2/LGR8 Antibody (NLS4751)(1)

Publication using NLS4751

• Restucci B, Sgadari M, Fatone G et al. Immunoexpression of Relaxin and Its Receptors in Stifle Joints of Dogs with Cranial Cruciate Ligament Disease Animals 2022-03-23 [PMID: 35405809] (IF/IHC, WB, Canine)

Bioinformatics

• Gene Symbol: RXFP2
• Entrez:
  • 122042(Human)
  • 140498(Mouse)