Relaxin R2/LGR8 Antibody (1013901) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: IHC
• Clone: 1013901
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Relaxin R2/LGR8 Antibody (1013901) [Alexa Fluor® 647] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Relaxin R2
  Met1-Asn416
  Accession # Q8WXD0
• Specificity: Detects human RelaxinR2 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Relaxin R2/LGR8 Antibody (1013901) [Alexa Fluor® 647]

• G protein coupled receptor affecting testicular descent
• Gpr106
• GPR106G-protein coupled receptor 106
• Great
• GREATRelaxin family peptide receptor 2
• INSL3R
• leucine-rich repeat-containing G protein-coupled receptor 8
• Leucine-rich repeat-containing G-protein coupled receptor 8
• Lgr8
• LGR8.1
• LGR8G-protein coupled receptor affecting testicular descent
• Relaxin R2
• relaxin receptor 2
• relaxin/insulin-like family peptide receptor 2
• RelaxinR2
• RLN2R
• Rxfp2
• RXFPR2

Background

Relaxin R2 (also known as LGR8) is the G-protein coupled receptor (GPCR) for Relaxin, and may also be a receptor for INSL3. LGR8 can mediate the action of Relaxin through cAMP-dependent pathway distinct from structurally related insulin and insulin-like growth factor family ligand. Distribution of this receptor implicates its role in reproductive, brain, renal, cardiovascular and other functions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.