Reduced Folate Carrier/SLC19A1 Antibody (890513) [Allophycocyanin]

• Applications: Flow
• Clone: 890513
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Reduced Folate Carrier/SLC19A1 Antibody (890513) [Allophycocyanin] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human Reduced Folate Carrier/SLC19A1
  Met1-Gln591
  Accession # P41440
• Specificity: Stains human Reduced Folate Carrier/SLC19A1 transfectants but not irrelevant transfectants in flow cytometry.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC19A1
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

SLC19A1, also known as Reduced Folate Carrier protein, is a multi-pass transmembrane transporter that is involved in the regulation of intracellular concentrations of folate. There is an association between idiopathic Recurrent Spontaneous Abortion (RSA) and SLC19A1 polymorphisms that may be useful biomarkers for RSA risk. Three transcript variants encoding different isoforms have been found for this gene. Human and mouse SLC19A1 share only 58% amino acid (aa) sequence identity, with considerable divergence over the C-terminal 100 aa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC19A1