PRMT2 Antibody [FITC]

Product Discontinued

PRMT2 Antibody [FITC] Summary

• Immunogen: Synthetic peptide made to an internal portion of human PRMT2 (within residues 380-433). [Swiss-Prot# P55345]
• Specificity: This is specific for PRMT2, and may also recognize a homodimer at ~98 kDa as referenced in Chao et al (3).
• Predicted Species: Bovine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PRMT2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
• Application Notes: This PRMT2 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where bands are observed at ~47 kDa and ~98 kDa. In ICC/IF diffuse cytoplasmic staining with some nuclear reactivity was observed in HeLa cells.
  
  The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PRMT2 Antibody [FITC]

• EC 2.1.1.-
• EC 2.1.1.125
• Histone-arginine N-methyltransferase PRMT2
• HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1
• HMT1 hnRNP methyltransferase-like 1 (S. cerevisiae)
• HMT1 hnRNP methyltransferase-like 1
• HMT1
• HRMT1L1PRMT2 beta
• MGC111373
• PRMT2 alpha
• PRMT2 gamma
• protein arginine methyltransferase 2
• protein arginine N-methyltransferase 2

Background

PRMT2 is a member of the protein arginine N-methyltransferase family that has been shown to be both an androgen receptor (AR)-associated coactivator and an estrogen receptor. PRMT2 expression is upregulated in the lung under hypoxic conditions, and has been shown to inhibit cell activation and promote programmed cell death through a NF-kappaB-dependent mechanism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PRMT2