PPAPDC3 Antibody - BSA Free

Western Blot: PPAPDC3 Antibody [NBP1-76246] - Mouse heart tissue lysate with PPAPDC3 antibody at (A) 1 and (B) 2 ug/mL.

Immunocytochemistry/Immunofluorescence: PPAPDC3 Antibody [NBP1-76246] - Mouse heart tissue with PPAPDC3 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

PPAPDC3 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide from near the amino of terminus human PPAPDC3. The immunogen is located within the first 50 amino acids of PPAPDC3. Amino Acid Squence: PPKGGPEPRSSGRKASGPS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLPP7
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  PPAPDC3 Peptide (NBP1-76246PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for PPAPDC3 Antibody - BSA Free

• C9orf67
• chromosome 9 open reading frame 67
• EC 3.1.3
• EC 3.1.3.-
• FLJ14662
• KIAA0515
• MGC12921
• NET39
• phosphatidic acid phosphatase type 2 domain containing 3
• Phosphatidic acid phosphatase type 2 domain-containing protein 3
• probable lipid phosphate phosphatase PPAPDC3

Background

PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLPP7
• Uniprot:
  • EAW87966(Human)