P2Y6/P2RY6 Antibody (JG37-77)

Western Blot: P2Y6/P2RY6 Antibody (JG37-77) [NBP2-75604] - Analysis of P2Y6 on SK-Br-3 (1) and A549 (2) cell lysate using anti-P2Y6 antibody at 1/1,000 dilution.

Immunohistochemistry-Paraffin: P2Y6/P2RY6 Antibody (JG37-77) [NBP2-75604] - Analysis of paraffin-embedded human kidney tissue using anti-P2Y6 antibody. Counter stained with hematoxylin.

Immunohistochemistry-Paraffin: P2Y6/P2RY6 Antibody (JG37-77) [NBP2-75604] - Analysis of paraffin-embedded human liver tissue using anti-P2Y6 antibody. Counter stained with hematoxylin.

Immunohistochemistry-Paraffin: P2Y6/P2RY6 Antibody (JG37-77) [NBP2-75604] - Analysis of paraffin-embedded human colon tissue using anti-P2Y6 antibody. Counter stained with hematoxylin.

Product Discontinued

P2Y6/P2RY6 Antibody (JG37-77) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide within Human P2Y6/P2RY6 aa 279-328 / 328. (SwissProt: Q15077 Human)
• Localization: Cell membrane.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: P2RY6
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Immunoprecipitation 1:10-1:50
  • Western Blot 1:500-1:2000
• Theoretical MW: 36 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for P2Y6/P2RY6 Antibody (JG37-77)

• G-coupled nucleotide receptor
• MGC15335
• P2 purinoceptor
• P2RY6
• P2Y6 receptor
• P2Y6
• P2Y6P2Y purinoceptor 6
• pyrimidinergic receptor P2Y, G-protein coupled, 6

Background

The purinergic receptor P2Y6 (P2RY6) is a member of the Purinergic Receptor subfamily. P2 receptors mediate a wide variety of physiologic effects in response to extracellular nucleotides. P2Y6 is believed to play a role in placental function and innate immune defense. P2Y6 expression has been documented in various blood cells, bone marrow, brain, colon, heart, kidney, ovary, placenta, spleen,and thymus. ESTs have been isolated from cervix, embryo, eye, kidney, liver/spleen, placenta, and vessel libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: P2RY6