METTL7A Antibody

Images

 
Western Blot: METTL7A Antibody [NBP1-77336] - MCF cell lysate with MettL7A antibody at 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: METTL7A Antibody [NBP1-77336] - MCF7 cells with MettL7a antibody at 2 ug/ml.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

METTL7A Antibody Summary

Immunogen
Antibody was raised against a 13 amino acid synthetic peptide near the center of human MettL7A. The immunogen is located within amino acids 130 - 180 of MettL7A.
Specificity
At least two isoforms of MettL7A are known to exist. This antibody is predicted to not cross-react with MettL7B.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
METTL7A
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
Control Peptide
METTL7A Peptide (NBP1-77336PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for METTL7A Antibody

  • AAM-B
  • DKFZp586A0522
  • EC 2.1.1
  • EC 2.1.1.-
  • methyltransferase like 7A
  • methyltransferase-like protein 7A
  • Protein AAM-B

Background

MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. At least two isoforms of MettL7A are known to exist. This antibody is predicted to not cross-react with MettL7B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol METTL7A
Uniprot